Does using one cheat wreck your trophies for good or just till you reload? Dont wanna lose my 100% run lol

Your 100% run is safe. Cheats only switch off achievements and trophies for the current session, the moment you enter one, they don't permanently flag the save. So keep a clean save for your real progress and mess around with cheats on a separate one. Want trophies counting again? Just reload a save from before you touched a cheat that session. Nothing's bricked.